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CAS No.: 516-35-8

牛磺鹅去氧胆酸 Catalog No. CSN13130

Synonyms: 12-Deoxycholyltaurine;Taurochenodeoxycholic Acid D5;Taurochenodeoxycholic Acid MaxSpec® Standard

Taurochenodeoxycholic acid-d5 is a natural product.

规格	价格	促销价格	库存	数量

400-920-2911

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靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Chenodeoxycholic acid, also named as chenic acid, is one of the major biliary bile acids in human. In vitro studies, chenodeoxycholic acid could effectively inhibit the proteolytic activity of pepsin against n-APDT. In vivo studies, it was found that neonates would have a significantly greater pool of chenodeoxycholic acid (CDCA) when 0.25% CDCA was fed to pregnant rats, while CDCA would have no hepatotoxic effects on maternal and neonatal. Besides this, chronic administration of chenodeoxycholic acid could contribute to the increasing of cholesterol saturation in bile of dogs when given 200 mg/day for 15 days.
动物研究
剂量
Mice: 300 mg/kg/day^[3] (p.o.)

给药途径
p.o.
参考文献

动物研究
剂量	Mice: 300 mg/kg/day^[3] (p.o.)
给药途径	p.o.

[1] Wang X, Zhang Z, et al. Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK-dependent pathway. Eur J Pharmacol. 2016 Sep 5;786:109-115.
[2] Uchida A, Yamada T, et al. Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation. Am J Physiol. 1997 May;272(5 Pt 1):G1249-57.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.0012 mL
- 10.0059 mL
- 20.0119 mL
- 5 mM
- 0.4002 mL
- 2.0012 mL
- 4.0024 mL
- 10 mM
- 0.2001 mL
- 1.0006 mL
- 2.0012 mL

技术信息

CAS号

516-35-8

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C26H45NO6S

运输

蓝冰

分子量

499.70

别名

12-Deoxycholyltaurine;Taurochenodeoxycholic Acid D5;Taurochenodeoxycholic Acid MaxSpec® Standard;Taurochenodeoxycholate;TCDCA;牛磺鹅去氧胆酸

溶解度

DMSO	220.0 mg/mL (440.3 mM)
Water	320.0 mg/mL (640.4 mM)

动物实验配方

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